A colleague of mine who develops therapeutic MAbs shared this with me ... hope
this helps Scott:
KabatMan; http://www.bioinf.org.uk/abs/simkab.html
This is the old 'Kabat' database which has not been updated since 2000
Abysis; http://www.abysis.org/abysis/index.html
Wonderful resource, one would use the 'Search' tools for what the posting asked
Thera-SAbDab; http://opig.stats.ox.ac.uk/webapps/newsabdab/therasabdab/search/
Database of therapeutic antibodies which have been assigned an International
Nonproprietary Name (INN; assignment typically occurs at some point in phase I
or II)
IMGT V-Quest; https://www.imgt.org/IMGT_vquest/input
For germline assignment. Many other tools/databases on IMGT site.
IgBlast; https://www.ncbi.nlm.nih.gov/igblast/
Also for germline assignment. References IMGT database
I think the above is most of them. You can search against a sequence in each of
the above, but if the desire is to download a database, options may be more
limited.
-----Original Message-----
From: Antibody Discussion Forum <email obscured>> On Behalf Of
Brown, Scott A
Sent: Wednesday, March 9, 2022 10:58 AM
To: <email obscured>
Subject: [EXTERNAL] [ABRF Ab Forum] database?
Good morning all,
Is there a database for antibody sequences (mouse, human, etc) that can be
searched, aligned, etc? It seems that Pubmed is limited and not very easy to
do. I would love to compile several CDR loops from various antibodies.
Hope everyone is having a great 2022!
Best,
Scott
Scott Brown, Ph.D.
Director of Immunologic Reagent Facility Department of Immunology St. Jude
Children's Res. Hosp.
w. (901) 595-4067
c. (901) 674-9960
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